Abstract: Under the wave of digital transformation, refined oil sales enterprises have an increasingly urgent need for efficient and reliable network architecture. This article focuses on the application practice of IPv6+SD-WAN technology in refined oil sales enterprises, analyzing the address capacity, security management, and traffic monitoring capabilities of IPv6 protocol, as well as the ability improvement brought by SD-WAN technology to network allocation, application experience, and other aspects. It elaborates on the changes brought by the integration of the two to the network architecture and business optimization of refined oil sales enterprises. Practice has shown that IPv6+SD-WAN technology can help enterprises achieve efficient network transmission, meet diverse business needs such as dynamic business segmentation and link redundancy guarantee, ensure stable operation of key businesses through network slicing, and optimize network performance through flow detection. At the same time, at the enterprise operation and maintenance level, this technology simplifies management processes and improves operation and maintenance efficiency. This article provides a detailed introduction to a specific application case of a refined oil sales enterprise, explores the deployment strategy and effectiveness of IPv6+SD-WAN, analyzes deployment strategies under different situations, and provides a reference paradigm for similar enterprises, which is of great significance for promoting the digital development of the refined oil sales industry.